首页> Journal of proteome research> MultiOmicsAgent: Guided Extreme Gradient-Boosted Decision Trees-Based Approaches for Biomarker-Candidate Discovery in Multiomics Data.

MultiOmicsAgent: Guided Extreme Gradient-Boosted Decision Trees-Based Approaches for Biomarker-Candidate Discovery in Multiomics Data.

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第一作者： Jens,Settelmeier

第一单位： Institute of Translational Medicine at the Department of Health Sciences and Technology, ETH, Zurich 8093, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.

作者： Jens,Settelmeier ^[1] ; Sandra,Goetze ^[2] ; Julia,Boshart ^[3] ; Jianbo,Fu ^[2] ; Amanda,Khoo ^[3] ; Sebastian N,Steiner ^[3] ; Martin,Gesell ^[3] ; Jacqueline,Hammer ^[3] ; Peter J,Schüffler ^[4] ; Diyora,Salimova ^[5] ; Patrick G A,Pedrioli ^[6] ; Bernd,Wollscheid ^[2]

作者单位： Institute of Translational Medicine at the Department of Health Sciences and Technology, ETH, Zurich 8093, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland. ^[1] Institute of Translational Medicine at the Department of Health Sciences and Technology, ETH, Zurich 8093, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.;ETH PHRT Swiss Multi-Omics Center (SMOC), Zurich 8093, Switzerland. ^[2] Institute of Translational Medicine at the Department of Health Sciences and Technology, ETH, Zurich 8093, Switzerland. ^[3] Institute of Pathology, TUM School of Medicine and Health, Technical University of Munich, Munich 81675, Germany. ^[4] Department for Applied Mathematics, Albert-Ludwigs-University of Freiburg, Freiburg 79104, Germany. ^[5] Institute of Translational Medicine at the Department of Health Sciences and Technology, ETH, Zurich 8093, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.;ETH PHRT Swiss Multi-Omics Center (SMOC), Zurich 8093, Switzerland.;Department of Biology, ETH, Zurich 8093, Switzerland. ^[6]

关键词 Python tool biomarker discovery extreme gradient-boosted decision trees machine learning multiomics

医学主题词决策树(Decision Trees);人类(Humans);软件(Software);蛋白质组学(Proteomics)

DOI 10.1021/acs.jproteome.4c01066

PMID 40415340

发布时间 2025-06-12

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