首页> Antibiotics (Basel, Switzerland)> Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms-Genome Proneness-Compensatory Adaptations.

Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms-Genome Proneness-Compensatory Adaptations.

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第一作者： Eleonora,Chines

第一单位： Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.;Department of Public Health, Experimental, and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.

作者： Eleonora,Chines ^[1] ; Gaia,Vertillo Aluisio ^[2] ; Maria Lina,Mezzatesta ^[2] ; Maria,Santagati ^[2] ; Viviana,Cafiso ^[2]

作者单位： Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.;Department of Public Health, Experimental, and Forensic Medicine, University of Pavia, 27100 Pavia, Italy. ^[1] Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy. ^[2]

关键词 DAP/GLY MOA-related AMR mechanisms compensatory mutations essential genes fitness cost omic basis genome proneness transcription-shifts virulomics

DOI 10.3390/antibiotics14050465

PMID 40426532

发布时间 2025-05-31

基金项目

PE00000007 INF-ACT/EU funding with the MUR PNRR "EXTENDED PARTNERSHIP INITIATIVE ON EMERGENCE INFECTIOUS DISEASE" PIACERI 2024-2026/Linea intervento 1 Progetti di Ricerca Collaborativa PIACERI 2024-2026" from the University of Catania, Italy

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Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms-Genome Proneness-Compensatory Adaptations.

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Mutation- and Transcription-Driven Omic Burden of Daptomycin/Dalbavancin-R and Glycopeptide-RS Fitness Costs in High-Risk MRSA: A Nexus in Antimicrobial Resistance Mechanisms-Genome Proneness-Compensatory Adaptations.

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