换一批New Genomics Discoveries Across the Bipolar Disorder Spectrum Implicate Neurobiological and Developmental Pathways.
第一作者：
Kevin S,O'Connell
第一单位：
Center for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: kevin.oconnell@medisin.uio.no.
作者：
Kevin S,O'Connell [1]
;
Rolf,Adolfsson [2]
;
Till F M,Andlauer [3]
;
Michael,Bauer [4]
;
Bernhaud,Baune [5]
;
Joanna M,Biernacka [6]
;
Bernardo,Carpiniello [7]
;
Sven,Cichon [8]
;
Nick,Craddock [9]
;
Alfredo B,Cuellar-Barboza [10]
;
Udo,Dannlowski [11]
;
Franziska,Degenhardt [12]
;
Dimitris,Dikeos [13]
;
Panagiotis,Ferentinos [14]
;
Andreas J,Forstner [15]
;
Mark A,Frye [16]
;
Janice M,Fullerton [17]
;
Maria,Grigoroiu-Serbanescu [18]
;
José,Guzman-Parra [19]
;
Lisa,Jones [20]
;
Lina,Jonsson [21]
;
Tilo,Kircher [22]
;
Manolis,Kogevinas [23]
;
Mikael,Landén [24]
;
Jolanta,Lissowska [25]
;
Christine,Lochner [26]
;
Mirko,Manchia [27]
;
Fermin,Mayoral [19]
;
Susan L,McElroy [28]
;
Nathaniel W,McGregor [29]
;
Andreas,Meyer-Lindenberg [30]
;
Philip B,Mitchell [31]
;
Bertram,Müller-Myhsok [32]
;
Markus M,Nöthen [33]
;
George P,Patrinos [34]
;
Joanna M,Pawlak [35]
;
Andreas,Reif [36]
;
Marcella,Rietschel [37]
;
Peter R,Schofield [31]
;
Thomas G,Schulze [38]
;
Alessandro,Serretti [39]
;
Jordan W,Smoller [40]
;
Alessio,Squassina [41]
;
Dan J,Stein [42]
;
Fabian,Streit [43]
;
Beata,Świątkowska [44]
;
Leonardo,Tondo [45]
;
Eduard,Vieta [46]
;
Irwin D,Waldman [47]
;
Anders M,Dale [48]
;
Ole A,Andreassen [49]
;
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
作者单位：
Center for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: kevin.oconnell@medisin.uio.no.
[1]
Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, Sweden.
[2]
Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
[3]
Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
[4]
Department of Psychiatry, University of Münster, Münster, Germany; Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia.
[5]
Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.
[6]
Unit of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; Unit of Clinical Psychiatry, Department of Medicine, University Hospital Agency of Cagliari, Cagliari, Italy.
[7]
Department of Biomedicine, University of Basel, Basel, Switzerland; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany.
[8]
National Centre for Mental Health, Cardiff University, Cardiff, United Kingdom.
[9]
Department of Psychiatry, Universidad Autónoma de Nuevo León, Monterrey, Mexico; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.
[10]
Institute for Translational Psychiatry, University of Münster, Münster, Germany.
[11]
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany.
[12]
National and Kapodistrian University of Athens, 1st Department of Psychiatry, Eginition Hospital, Athens, Greece.
[13]
National and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece; Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.
[14]
Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany; Department of Psychiatry, Marburg University, Marburg, Germany.
[15]
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.
[16]
Neuroscience Research Australia, Sydney, New South Wales, Australia; School of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, New South Wales, Australia.
[17]
Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania.
[18]
Mental Health Department, University Regional Hospital, Biomedicine Institute, Málaga, Spain.
[19]
Three Counties Medical School, University of Worcester, Worcester, United Kingdom.
[20]
Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
[21]
Department of Psychiatry, Marburg University, Marburg, Germany.
[22]
ISGlobal, Barcelona, Spain.
[23]
Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[24]
Cancer Epidemiology and Prevention, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
[25]
South African Medical Research Council Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
[26]
Unit of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; Unit of Clinical Psychiatry, Department of Medicine, University Hospital Agency of Cagliari, Cagliari, Italy; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
[27]
Research Institute, Lindner Center of HOPE, Mason, Ohio.
[28]
Human and Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.
[29]
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; German Centre for Mental Health, Germany.
[30]
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine & Health, University of New South Wales, Sydney, New South Wales, Australia.
[31]
Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany; University of Liverpool, Liverpool, United Kingdom.
[32]
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
[33]
University of Patras, School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, Patras, Greece; United Arab Emirates University, College of Medicine and Health Sciences, Department of Genetics and Genomics, Al-Ain, Abu Dhabi, United Arab Emirates; United Arab Emirates University, Zayed Center for Health Sciences, Al-Ain, Abu Dhabi, United Arab Emirates; Erasmus University Medical Center, Faculty of Medicine and Health Sciences, Department of Pathology, Clinical Bioinformatics unit, Rotterdam, the Netherlands.
[34]
Department of Psychiatry, Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poznań, Poland.
[35]
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt am Main, Germany.
[36]
Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, State University of New York Upstate Medical University, Syracuse, New York.
[37]
Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, State University of New York Upstate Medical University, Syracuse, New York; Institute of Psychiatric Phenomics and Genomics, Ludwig Maximilian University of Munich University Hospital, Ludwig Maximilian University of Munich, Munich, Germany; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
[38]
Department of Medicine and Surgery, Kore University of Enna, Enna, Italy; Oasi Research Institute, Istituto di Ricovero e Cura a Carattere Scientifico, Troina, Italy.
[39]
Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
[40]
Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
[41]
South African Medical Research Council Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
[42]
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt am Main, Germany; Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; German Center for Mental Health, Partner Site Mannheim-Heidelberg-Ulm, Germany.
[43]
Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland.
[44]
Lucio Bini Mood Disorder Center, Cagliari, Italy; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
[45]
Institute of Neuroscience, University of Barcelona, Barcelona, Spain; Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; CIBERSAM, Barcelona, Spain.
[46]
Department of Psychology, Emory University, Atlanta, Georgia.
[47]
Multimodal Imaging Laboratory, University of California San Diego, La Jolla, California; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California.
[48]
Center for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; KG Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: o.a.andreassen@medisin.uio.no.
[49]
医学主题词
人类(Humans);双相情感障碍(Bipolar Disorder);全基因组关联研究(Genome-Wide Association Study);基因组学(Genomics);疾病遗传易感性(Genetic Predisposition to Disease);多因子遗传(Multifactorial Inheritance)
DOI
10.1016/j.biopsych.2025.05.020
PMID
40456304
发布时间
2026-05-28
- 浏览0
Biological psychiatry
Biological psychiatry
302-310页
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