An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference.
第一作者:
Robel,Alemu
第一单位:
UCLA Anderson School of Management, Los Angeles, CA, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Adelaide Medical School, University of Adelaide, Adelaide, Australia.
作者:
Robel,Alemu [1]
;
Anastasia,Terskaya [2]
;
Matthew,Howell [3]
;
Junming,Guan [3]
;
Harry,Sands [4]
;
Aaron,Kleinman [5]
;
23andMe Research Team [6]
;
David,Bann [6]
;
Tim,Morris [6]
;
George B,Ploubidis [7]
;
Emla,Fitzsimons [8]
;
Kathleen Mullan,Harris [9]
;
Avshalom,Caspi [10]
;
David L,Corcoran [9]
;
Terrie E,Moffitt [11]
;
Richie,Poulton [12]
;
Karen,Sugden [12]
;
Benjamin S,Williams [13]
;
Andrew,Steptoe [14]
;
Olesya,Ajnakina [15]
;
Uku,Vainik [16]
;
Tõnu,Esko [17]
;
Estonian Biobank Research Team [18]
;
Archie,Campbell [19]
;
Caroline,Hayward [19]
;
William G,Iacono [19]
;
Matt,McGue [20]
;
Robert F,Krueger [20]
;
Anna R,Docherty [21]
;
Andrey A,Shabalin [22]
;
Ralph,Hertwig [23]
;
Philipp,Koellinger [24]
;
David,Richter [25]
;
Jan,Goebel [25]
;
Rafael,Ahlskog [26]
;
Sven,Oskarsson [27]
;
Patrik K E,Magnusson [28]
;
K Paige,Harden [29]
;
Elliot M,Tucker-Drob [30]
;
Charlotte K L,Pahnke [31]
;
Carlo,Maj [32]
;
Frank M,Spinath [33]
;
Pamela,Herd [34]
;
Jeremy,Freese [35]
;
David,Laibson [3]
;
Michelle N,Meyer [36]
;
Jonathan,Jala [37]
;
David,Cesarini [38]
;
Alexander Strudwick,Young [39]
;
Patrick,Turley [40]
;
Daniel J,Benjamin ;
Aysu,Okbay
作者单位:
UCLA Anderson School of Management, Los Angeles, CA, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Adelaide Medical School, University of Adelaide, Adelaide, Australia.
[1]
Department of Economics and Institut d'Economia de Barcelona (IEB), University of Barcelona, Carrer de John Maynard Keynes, 1, 11, 08034, Barcelona Spain.
[2]
UCLA Anderson School of Management, Los Angeles, CA, USA.
[3]
Bucknell University, Lewisburg, PA, USA.
[4]
23andMe, Inc., Mountain View, CA, USA.
[5]
Centre for Longitudinal Studies, Social Research Institute, University College London, London, UK.
[6]
Centre for Longitudinal Studies, University College London Institute of Education, London, England, WC1H 0NU, UK.
[7]
Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Sociology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
[8]
Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.;Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.;Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.;Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
[9]
Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
[10]
Dunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand.
[11]
Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
[12]
Department of Behavioural Science and Health, University College London, London, UK.
[13]
Department of Behavioural Science and Health, University College London, London, UK.;Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
[14]
Institute of Genomics, University of Tartu, Tartu, Estonia.;Institute of Psychology, University of Tartu, Estonia.;Montreal Neurological Institute, McGill University, Canada.
[15]
Institute of Genomics, University of Tartu, Tartu, Estonia.;Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[16]
Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.;Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh Bioquarter, 5-7 Little France Road, Edinburgh, EH16 4UX, United Kingdom.
[17]
MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.
[18]
Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
[19]
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.
[20]
Max-Planck Institute for Human Development, Center for Adaptive Rationality, Berlin, Germany.
[21]
Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.;DeSci Foundation, Geneva, Switzerland.
[22]
Educational Science and Psychology, Freie Universitaet Berlin, Berlin, Germany.;SHARE Berlin Institute, Berlin, Germany.
[23]
German Socio-Economic Panel Study, Deutsches Institut für Wirtschaftsforschung (DIW Berlin), Berlin, Germany.
[24]
Department of Government, Uppsala University, Uppsala, Sweden.
[25]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[26]
Department of Psychology, The University of Texas at Austin, Austin, TX, USA.;Population Research Center, The University of Texas at Austin, Austin, TX, USA.
[27]
Department of Psychology, The University of Texas at Austin, Austin, TX, USA.;Population Research Center, The University of Texas at Austin, Austin, TX, USA.;Center on Aging and Population Sciences, The University of Texas at Austin, Austin, TX, USA.
[28]
Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
[29]
Center for Human Genetics, University of Marburg; Institute for Genomic Statistics and Bioinformatics, University of Bonn, Germany.
[30]
Department of Psychology, Saarland University, Germany.
[31]
McCourt School of Public Policy, Georgetown University, Washington, DC, USA.
[32]
Department of Sociology, Stanford University.
[33]
National Bureau of Economic Research, Cambridge, MA, USA.;Department of Economics, Harvard University, Cambridge, MA, USA.
[34]
Center for Translational Bioethics and Health Care Policy, Geisinger Health System, Danville, PA, USA.
[35]
National Bureau of Economic Research, Cambridge, MA, USA.;Department of Economics, New York University, New York, NY.
[36]
UCLA Anderson School of Management, Los Angeles, CA, USA.;Human Genetics Department, UCLA David Geffen School of Medicine, Los Angeles, CA, US.
[37]
Department of Economics, University of Southern California, Los Angeles, CA, USA.;Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
[38]
UCLA Anderson School of Management, Los Angeles, CA, USA.;National Bureau of Economic Research, Cambridge, MA, USA.;Human Genetics Department, UCLA David Geffen School of Medicine, Los Angeles, CA, US.
[39]
Genetic Epidemiology, Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.
[40]
DOI
10.1101/2025.05.14.653986
PMID
40463245
发布时间
2025-11-24
基金项目
R01 AG077742/AG/NIA NIH HHS/United States
R00 AG062787/AG/NIA NIH HHS/United States
R01 AG083379/AG/NIA NIH HHS/United States
U19 AG051426/AG/NIA NIH HHS/United States
R01 AG053217/AG/NIA NIH HHS/United States
R01 AG042568/AG/NIA NIH HHS/United States
R24 AG065184/AG/NIA NIH HHS/United States
R01 AG081518/AG/NIA NIH HHS/United States
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