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Loss of colonic fidelity enables multilineage plasticity and metastasis.

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第一作者: Patrizia,Cammareri
第一单位: Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.
作者单位: Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. [1] Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;Cancer Research UK Scotland Institute, Glasgow, UK. [2] Molecular Digestive Oncology, Department of Oncology, Katholieke Universiteit Leuven, Leuven, Belgium. [3] Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. [4] MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. [5] Cancer Research UK Scotland Institute, Glasgow, UK. [6] Cancer Research UK Scotland Institute, Glasgow, UK.;School of Cancer Sciences, University of Glasgow, Glasgow, UK. [7] School of Cancer Sciences, University of Glasgow, Glasgow, UK. [8] Cancer Research UK Scotland Institute, Glasgow, UK.;The Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK. [9] Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK.;MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. [10] Cancer Research UK Scotland Institute, Glasgow, UK.;School of Cancer Sciences, University of Glasgow, Glasgow, UK.;University Department of Surgery, Glasgow Royal Infirmary, Glasgow, UK. [11] Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. kevin.myant@ed.ac.uk.;Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Edinburgh, UK. kevin.myant@ed.ac.uk. [12]
DOI 10.1038/s41586-025-09125-5
PMID 40468074
发布时间 2026-04-15
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