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Unveiling alternative splicing dynamics in activated T lymphocytes and their implications for immune checkpoint blockade efficacy.

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第一作者： Elad,Zisman

第一单位： The Lautenberg Center for Immunology and Cancer Research, The Faculty of Medicine Hebrew University of Jerusalem, Jerusalem, Israel.

作者： Elad,Zisman ^[1] ; Ori,Stern ^[1] ; Reyut,Lewis ^[1] ; Shay,Tzaban ^[1] ; Thomas,Eisenhaure ^[2] ; Sarah E,Henrickson ^[3] ; Moshe,Sade-Feldman ^[2] ; Shira,Silberman-Klein ^[4] ; Galit,Eisenberg ^[5] ; Nir,Hacohen ^[2] ; Keren,Yizhak ^[6] ; Michal,Lotem ^[5]

作者单位： The Lautenberg Center for Immunology and Cancer Research, The Faculty of Medicine Hebrew University of Jerusalem, Jerusalem, Israel. ^[1] Broad Institute of MIT and Harvard, Division of Allergy Immunology, Boston, MA, USA. ^[2] Department of Pediatrics, the Children's Hospital of Philadelphia, Philadelphia, and Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[3] The Lautenberg Center for Immunology and Cancer Research, The Faculty of Medicine Hebrew University of Jerusalem, Jerusalem, Israel.;Center for Melanoma and Cancer Immunotherapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel. ^[4] The Lautenberg Center for Immunology and Cancer Research, The Faculty of Medicine Hebrew University of Jerusalem, Jerusalem, Israel.;Center for Melanoma and Cancer Immunotherapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel.;Hadassah Cancer Research Institute, Hadassah Hebrew University Medical Center, Jerusalem, Israel. ^[5] Technion Israel Institute of Technology, Haifa, Israel. ^[6]

关键词 Biological sciences Immune response Immunology Molecular biology

DOI 10.1016/j.isci.2025.112434

PMID 40469104

发布时间 2025-06-07

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Unveiling alternative splicing dynamics in activated T lymphocytes and their implications for immune checkpoint blockade efficacy.

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Unveiling alternative splicing dynamics in activated T lymphocytes and their implications for immune checkpoint blockade efficacy.

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