首页> Molecular pharmaceutics> Intratumoral Immunotherapy with Cowpea Mosaic Virus and Interleukin-12 Eliminates Established Treated Tumors and Generates Robust Systemic Immunity to Suppress the Growth of Untreated Metastatic Tumors.

Intratumoral Immunotherapy with Cowpea Mosaic Virus and Interleukin-12 Eliminates Established Treated Tumors and Generates Robust Systemic Immunity to Suppress the Growth of Untreated Metastatic Tumors.

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第一作者： Alex,Misiaszek

第一单位： Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States.

作者： Alex,Misiaszek ^[1] ; Alicia M,Santos ^[1] ; Greg W,Ho ^[1] ; Jennifer,Fields ^[1] ; Kevine Silihe,Kamga ^[1] ; Radu,Stan ^[2] ; Jessica F,Affonso De Oliveira ^[3] ; Nicole F,Steinmetz ; Steven,Fiering

作者单位： Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States. ^[1] Dartmouth Cancer Center, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States.;Department of Biochemistry and Cell Biology, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States. ^[2] Department of Microbiology and Immunology, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States.;Dartmouth Cancer Center, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, United States. ^[3]

关键词 IL-12 cowpea mosaic virus electroporation in vivo transfection intratumoral immunotherapy