第一单位:
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. charlotte.brierley@imm.ox.ac.uk.;Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. charlotte.brierley@imm.ox.ac.uk.;Department of Haematology, OUH NHS Foundation Trust, Oxford, UK. charlotte.brierley@imm.ox.ac.uk.
作者:
Charlotte K,Brierley [1]
;
Bon Ham,Yip [2]
;
Giulia,Orlando [3]
;
Jeremy,Wen [2]
;
Sean,Wen [3]
;
Harsh,Goyal [4]
;
Max,Levine [5]
;
G Maria,Jakobsdottir [6]
;
Avraam,Tapinos [6]
;
Alex J,Cornish [7]
;
Antonio,Rodriguez-Romera [3]
;
Alba,Rodriguez-Meira [8]
;
Matthew,Bashton [9]
;
Angela,Hamblin [10]
;
Sally Ann,Clark [3]
;
Joseph C,Hamley [3]
;
Olivia,Fox [11]
;
Madalina,Giurgiu [12]
;
Jennifer,O'Sullivan [13]
;
Lauren,Murphy [3]
;
Assunta,Adamo [3]
;
Aude Anais,Olijnik [3]
;
Anitria,Cotton [2]
;
Emily,Hendrix [14]
;
Shilpa,Narina [14]
;
Shondra M,Pruett-Miller [14]
;
Amir,Enshaei [15]
;
Claire,Harrison [16]
;
Mark,Drummond [17]
;
Steven,Knapper [18]
;
Ayalew,Tefferi [19]
;
Iléana,Antony-Debré [20]
;
James,Davies [3]
;
Anton G,Henssen [12]
;
Supat,Thongjuea [3]
;
David C,Wedge [6]
;
Stefan N,Constantinescu [4]
;
Elli,Papaemmanuil [21]
;
Bethan,Psaila [22]
;
John D,Crispino [23]
;
Adam J,Mead [24]
作者单位:
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. charlotte.brierley@imm.ox.ac.uk.;Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. charlotte.brierley@imm.ox.ac.uk.;Department of Haematology, OUH NHS Foundation Trust, Oxford, UK. charlotte.brierley@imm.ox.ac.uk.
[1]
Division of Experimental Haematology, St Jude Children's Research Hospital, Memphis, TN, USA.
[2]
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
[3]
Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.;de Duve Institute, Université Catholique de Louvain, Brussels, Belgium.;Walloon Excellence in Life Sciences and Biotechnology (WELBIO) Department, WEL Research Institute, Wavre, Belgium.;Ludwig Institute for Cancer Research, Nuffield Department of Medicine, Oxford University, Oxford, UK.
[4]
Isabl Inc., New York, NY, USA.
[5]
Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.;Christie Hospital, The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
[6]
Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
[7]
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.;Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
[8]
The Hub for Biotechnology in the Built Environment, Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
[9]
Department of Haematology, OUH NHS Foundation Trust, Oxford, UK.
[10]
Oxford Regional Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
[11]
Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.;Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.
[12]
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.;Department of Haematology, Guys and St Thomas' NHS Foundation Trust, London, UK.
[13]
Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA.;Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
[14]
Wolfson Childhood Cancer Research Centre, Newcastle University, Newcastle upon Tyne, UK.
[15]
Department of Haematology, Guys and St Thomas' NHS Foundation Trust, London, UK.
[16]
Department of Haematology, Beatson West of Scotland Cancer Centre, Glasgow, UK.
[17]
Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
[18]
Division of Hematology, Mayo Clinic, Rochester, MN, USA.
[19]
INSERM, UMR 1287, Villejuif, France.;Gustave Roussy, Villejuif, France.;Université Paris Saclay, Gif-sur-Yvette, France.
[20]
Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Isabl Inc., New York, NY, USA.
[21]
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.;Department of Haematology, OUH NHS Foundation Trust, Oxford, UK.;Ludwig Institute for Cancer Research, Nuffield Department of Medicine, Oxford University, Oxford, UK.
[22]
Division of Experimental Haematology, St Jude Children's Research Hospital, Memphis, TN, USA. john.crispino@stjude.org.
[23]
Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, UK. adam.mead@imm.ox.ac.uk.;Department of Haematology, OUH NHS Foundation Trust, Oxford, UK. adam.mead@imm.ox.ac.uk.
[24]
DOI
10.1038/s41588-025-02190-6
PMID
40490510
发布时间
2025-08-01