Sex-Specific Genetic Drivers of Memory, Executive Functioning, and Language Performance in Older Adults.
第一作者:
Jaclyn M,Eissman
第一单位:
Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, 37203, USA.;Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
作者:
Jaclyn M,Eissman [1]
;
Alexandra N,Regelson [2]
;
Skylar,Walters [2]
;
Derek B,Archer [1]
;
Alaina,Durant [2]
;
Shubhabrata,Mukherjee [3]
;
Michael L,Lee [3]
;
Seo-Eun,Choi [3]
;
Phoebe,Scollard [3]
;
Emily H,Trittschuh [4]
;
Jesse,Mez [5]
;
Moonil,Kang [6]
;
William S,Bush [7]
;
Brian W,Kunkle [8]
;
Adam C,Naj [9]
;
Katherine A,Gifford [10]
;
Murat,Bilgel [11]
;
Amanda B,Kuzma [12]
;
Alzheimer’s Disease Neuroimaging Initiative (ADNI) [8]
;
Alzheimer’s Disease Genetics Consortium (ADGC) [13]
;
Alzheimer’s Disease Sequencing Project (ADSP) [8]
;
Michael L,Cuccaro [6]
;
Carlos,Cruchaga [12]
;
Margaret A,Pericak-Vance [12]
;
Lindsay A,Farrer [14]
;
Li-San,Wang [14]
;
Gerard D,Schellenberg [7]
;
Badri N,Vardarajan [2]
;
Richard,Mayeux [15]
;
Jonathan L,Haines [16]
;
Angela L,Jefferson [17]
;
Walter A,Kukull [18]
;
C Dirk,Keene [8]
;
Andrew J,Saykin [19]
;
Paul M,Thompson [20]
;
Eden R,Martin [21]
;
Marilyn S,Albert [22]
;
Sterling C,Johnson [23]
;
Corinne D,Engelman [23]
;
Luigi,Ferrucci [23]
;
David A,Bennett [11]
;
Lisa L,Barnes [24]
;
Julie A,Schneider [3]
;
Susan M,Resnick [1]
;
Reisa A,Sperling [1]
;
Paul K,Crane ;
Timothy J,Hohman ;
Logan,Dumitrescu
作者单位:
Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, 37203, USA.;Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
[1]
Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, 37203, USA.
[2]
Department of Medicine, University of Washington, Seattle, WA, 98195, USA.
[3]
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, 98195, USA.;VA Puget Sound Health Care System, GRECC, Seattle, WA, 98108, USA.
[4]
Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.
[5]
Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.;Department of Biostatistics, Boston University School of Public Health, Boston, MA, 02118, USA.;Department of Medicine Biomedical Genetics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.
[6]
Cleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
[7]
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
[8]
Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.;Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
[9]
Department of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 02118, USA.
[10]
Laboratory of Behavioral Neuroscience National Institute on Aging, Baltimore, MD, 21224, USA.
[11]
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
[12]
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA.;NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, 63108, USA.
[13]
Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, 10032, USA.;Gertrude H. Sergievsky Center, Columbia University, New York, NY, 10032, USA.;Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
[14]
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, 98195, USA.
[15]
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.
[16]
Department of Radiology and Imaging Services, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.;Department of Medical and Molecular Genetics, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA.;Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
[17]
Imaging Genetics Center, Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
[18]
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
[19]
Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
[20]
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
[21]
Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.
[22]
Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA.
[23]
Department of Neurology, Harvard Medical School, Boston & Brigham and Women's Hospital, Boston, MA, 02115, USA.;Alzheimer's Disease Research Center, Massachusetts General Hospital, Charlestown, MA, 02129, USA.
[24]
DOI
10.1101/2025.05.26.25328369
PMID
40492063
发布时间
2025-06-24
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medRxiv
medRxiv
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