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Clinical relevance and methodological approach for the assessment of drug-drug interactions in cancer patients: a position statement from the Italian Association of Medical Oncology (AIOM) and the Italian Society of Pharmacology (SIF).

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第一作者： M,Del Re

第一单位： Saint Camillus International University of Health and Medical Sciences, Departmental Faculty of Medicine, Rome, Italy.

作者： M,Del Re ^[1] ; R,Roncato ^[2] ; A,Argentiero ^[3] ; L,Berrino ^[4] ; A,Botticelli ^[5] ; A,Capuano ^[4] ; S,Di Donato ^[6] ; S,Fogli ^[7] ; D,Marino ^[8] ; G,Rodriquenz ^[9] ; D,Speranza ^[10] ; F,Perrone ^[11] ; N,Silvestris ^[12] ; R,Danesi ^[13]

作者单位： Saint Camillus International University of Health and Medical Sciences, Departmental Faculty of Medicine, Rome, Italy. ^[1] Department of Medicine, University of Udine, Udine, Italy. ^[2] Medical Oncology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy. ^[3] Department of Experimental Medicine, Section of Pharmacology, University of Campania 'Luigi Vanvitelli', Naples, Italy. ^[4] Department of Radiological, Oncological and Pathological Science, Sapienza University of Rome, Rome, Italy. ^[5] Medical Oncology Department ASL Toscana Centro, Santo Stefano Hospital, Prato, Italy. ^[6] Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. ^[7] Department of Oncology, Ordine Mauriziano Hospital, Turin, Italy. ^[8] Division of Medical Oncology, Ospedale IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy. ^[9] Medical Oncology Unit, Department of Human Pathology 'G. Barresi', University of Messina, Messina, Italy. ^[10] Clinical Trial Unit, Istituto Nazionale Tumori, IRCCS, Fondazione G. Pascale, Naples, Italy. ^[11] Medical Oncology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy. Electronic address: silvestrisnicola@gmail.com. ^[12] Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. Electronic address: romano.danesi@unimi.it. ^[13]

关键词 DDI management framework anticancer treatment clinical pharmacology in oncology drug–drug interactions individualized cancer treatment