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High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression.

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第一作者： Stephen A,Murata

第一单位： Michigan State University College of Human Medicine, Grand Rapids, Michigan.;Pine Rest Christian Mental Health Services, Grand Rapids, Michigan.

作者： Stephen A,Murata ^[1] ; Zachary B,Madaj ^[2] ; Colt D,Capan ^[3] ; Ryan D,Sheldon ^[4] ; Rif S,El-Mallakh ^[5] ; Sagar V,Parikh ^[6] ; William V,Bobo ^[7] ; Fernando S,Goes ^[8] ; Owen M,Wolkowitz ^[9] ; Jennifer L,Vande Voort ^[10] ; Louis J,Nykamp ^[1] ; Balwinder,Singh ^[10] ; Gustavo C,Medeiros ^[11] ; Erik B,Nelson ^[12] ; Michael E,Thase ^[13] ; Gregory F,Oxenkrug ^[14] ; Mark A,Frye ^[10] ; John F,Greden ^[6] ; Eric D,Achtyes ^[15] ; Lena C,Brundin ^[16]

作者单位： Michigan State University College of Human Medicine, Grand Rapids, Michigan.;Pine Rest Christian Mental Health Services, Grand Rapids, Michigan. ^[1] Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan. ^[2] Mass Spectrometry Core, Van Andel Institute, Grand Rapids, Michigan.;Department for Neurodegenerative Sciences, Van Andel Research Institute, Grand Rapids, Michigan. ^[3] Mass Spectrometry Core, Van Andel Institute, Grand Rapids, Michigan. ^[4] University of Louisville, Louisville, Kentucky. ^[5] University of Michigan, Ann Arbor, Michigan. ^[6] Mayo Clinic, Jacksonville, Florida. ^[7] Johns Hopkins University, Baltimore, Maryland. ^[8] University of California San Francisco, San Francisco, California. ^[9] Mayo Clinic, Rochester, Minnesota. ^[10] University of Maryland School of Medicine, Baltimore, Maryland. ^[11] University of Cincinnati, Cincinnati, Ohio. ^[12] University of Pennsylvania, Philadelphia, Pennsylvania. ^[13] Tufts University School of Medicine, Boston, Massachusetts. ^[14] Michigan State University College of Human Medicine, Grand Rapids, Michigan.;Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, Michigan. ^[15] Department for Neurodegenerative Sciences, Van Andel Research Institute, Grand Rapids, Michigan. ^[16]

关键词 Anthranilic acid Bio-K Ketamine Kynurenine pathway Predictive biomarker Treatment-resistant depression

DOI 10.1016/j.bpsgos.2025.100503

PMID 40503326

发布时间 2025-06-13

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High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression.

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