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A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen.

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第一作者： Maria Letizia,Di Martino

第一单位： Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. ml.dimartino@imbim.uu.se.

作者： Maria Letizia,Di Martino ^[1] ; Laura,Jenniches ^[2] ; Anjeela,Bhetwal ^[3] ; Jens,Eriksson ^[3] ; Ana C C,Lopes ^[3] ; Angelika,Ntokaki ^[3] ; Martina,Pasqua ^[4] ; Magnus,Sundbom ^[5] ; Martin,Skogar ^[5] ; Wilhelm,Graf ^[5] ; Dominic-Luc,Webb ^[6] ; Per M,Hellström ^[6] ; André,Mateus ^[7] ; Lars,Barquist ^[8] ; Mikael E,Sellin ^[9]

作者单位： Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. ml.dimartino@imbim.uu.se. ^[1] Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany. laura.jenniches@helmholtz-hiri.de. ^[2] Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. ^[3] Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.;Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Rome, Italy. ^[4] Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. ^[5] Department of Medical Sciences, Uppsala University, Uppsala, Sweden. ^[6] Department of Chemistry, Umeå University, Umeå, Sweden.;The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden. ^[7] Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany. lars.barquist@helmholtz-hiri.de.;Faculty of Medicine, University of Würzburg, Würzburg, Germany. lars.barquist@helmholtz-hiri.de.;Department of Biology, University of Toronto, Mississauga, Ontario, Canada. lars.barquist@helmholtz-hiri.de.;Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada. lars.barquist@helmholtz-hiri.de. ^[8] Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. mikael.sellin@imbim.uu.se.;Science for Life Laboratory, Uppsala, Sweden. mikael.sellin@imbim.uu.se. ^[9]