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Association of valproic acid-related pharmacodynamics, pharmacokinetic pathways and transporter gene polymorphisms and antiepileptic efficacy in Chinese patients.

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第一作者： Linlin,Wang

第一单位： Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Department of Pharmacy, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen, China.

作者： Linlin,Wang ^[1] ; Guangting,Zeng ^[2] ; Jianqiang,Li ^[3] ; Huilan,Li ^[3] ; Jia,Luo ^[3] ; Zanling,Zhang ^[3]

作者单位： Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Department of Pharmacy, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen, China. ^[1] Department of Pharmacy, the First People's Hospital of Chenzhou, Xiangnan University, Chenzhou, China. ^[2] Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Department of Pharmacy, Fudan University Shanghai Cancer Center Xiamen Hospital, Xiamen, China.;Institute for Rational and Safe Medication Practices, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[3]

关键词 Valproic acid antiepileptic drug antiepileptic efficacy gene polymorphisms pharmacogenomics