Obesity promotes ARDS by modulating ceramide transfer protein-ceramide pathway and exacerbating oxidative stress/apoptosis in alveolar macrophages.
第一作者:
Yichan,Ao
第一单位:
Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
作者:
医学主题词
动物(Animals);神经酰胺类(Ceramides);氧化性应激(Oxidative Stress);肥胖症(Obesity);小鼠(Mice);细胞凋亡(Apoptosis);巨噬细胞, 肺泡(Macrophages, Alveolar);人类(Humans);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);活性氧(Reactive Oxygen Species);3T3-L1细胞(3T3-L1 Cells);信号传导(Signal Transduction);肺(Lung);脂多糖类(Lipopolysaccharides)
DOI
10.1007/s00018-025-05706-9
PMID
40537702
发布时间
2025-06-24
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