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The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8<sup>+</sup> T cell exhaustion.

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第一作者： Michael S,Dahabieh

第一单位： Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.;Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA.

作者： Michael S,Dahabieh ^[1] ; Lisa M,DeCamp ^[1] ; Brandon M,Oswald ^[1] ; Susan M,Kitchen-Goosen ^[1] ; Zhen,Fu ^[2] ; Matthew,Vos ^[1] ; Shelby E,Compton ^[1] ; Joseph,Longo ^[1] ; Nicole M,Foy ^[1] ; Kelsey S,Williams ^[1] ; Abigail E,Ellis ^[3] ; Amy,Johnson ^[3] ; Ibukunoluwa,Sodiya ^[4] ; Michael,Vincent ^[4] ; Hyoungjoo,Lee ^[4] ; Chen,Yao ^[5] ; Tuoqi,Wu ^[6] ; Ryan D,Sheldon ^[4] ; Connie M,Krawczyk ^[1] ; Russell G,Jones ^[7]

作者单位： Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.;Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA. ^[1] Bioinformatics and Biostatistics Core Facility, Van Andel Institute, Grand Rapids, MI, USA. ^[2] Mass Spectrometry Core Facility, Van Andel Institute, Grand Rapids, MI, USA. ^[3] Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.;Mass Spectrometry Core Facility, Van Andel Institute, Grand Rapids, MI, USA. ^[4] Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[5] Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA.;Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[6] Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA. russell.jones@vai.org.;Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA. russell.jones@vai.org. ^[7]