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A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins.

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第一作者: Sodbo,Sharapov
第一单位: MSU Institute for Artificial Intelligence, Lomonosov Moscow State University, Moscow, Russia.
作者单位: MSU Institute for Artificial Intelligence, Lomonosov Moscow State University, Moscow, Russia. [1] Genos Glycoscience Research Laboratory, Borongajska cesta 83H, Zagreb, Croatia. [2] Institute of Cytology and Genetics, Novosibirsk, Russia.;Novosibirsk State University, Novosibirsk, Russia. [3] Institute of Cytology and Genetics, Novosibirsk, Russia. [4] Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, St Thomas' Campus, Lambeth Palace Road, London, United Kingdom.;NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, United Kingdom. [5] Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany. [6] PolyOmica, 's-Hertogenbosch, Hertogenbosch, PA, The Netherlands. [7] Colon Cancer Genetics Group, Cancer Research UK Scotland Centre, Institute of Genetics & Cancer, Western General Hospital, The University of Edinburgh, Edinburgh, United Kingdom.;D-IAS, Danish Institute for Advanced Study, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9, Odense C, Denmark. [8] Institute of Cytology and Genetics, Novosibirsk, Russia.;PolyOmica, 's-Hertogenbosch, Hertogenbosch, PA, The Netherlands. [9] Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. [10] Institute of Cytology and Genetics, Novosibirsk, Russia.;Vavilov Institute of General Genetics Russian Academy of Sciences, Moscow, Russia. [11] Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, St Thomas' Campus, Lambeth Palace Road, London, United Kingdom. [12] St. Catherine Specialty Hospital, Ulica Kneza Branimira, 71E, Zagreb, Croatia.;University of Split School of Medicine, Split, Croatia.;University of Osijek School of Medicine, Osijek, Croatia. [13] Department of Anesthesiology and Multidisciplinary Paincentre, ZOL, Genk, Lanaken, Belgium.;Department of Anesthesiology and Pain Medicine, Maastricht University Medical Centre, P. Debyelaan 25, Maastricht, The Netherlands. [14] Unit of Animal Genomics, WELBIO, GIGA-R and Faculty of Veterinary Medicine, University of Liège, (B34) 1 Avenue de l'Hôpital, Liège, Belgium. [15] Department of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Doha, Qatar. [16] Centre Lemanique d'antalgie et neuromodulation - EHC, Morges, Switzerland. [17] MRC Unit for Lifelong Health & Ageing University College London, London, United Kingdom. [18] Colon Cancer Genetics Group, Cancer Research UK Scotland Centre, Institute of Genetics & Cancer, Western General Hospital, The University of Edinburgh, Edinburgh, United Kingdom. [19] Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam- Rehbruecke, 14558, Nuthetal, Germany.;German Center for Diabetes Research (DZD), Neuherberg, Germany.;Institute of Nutrition Science, University of Potsdam, Potsdam, Germany. [20] Institute of Cytology and Genetics, Novosibirsk, Russia.;Wellcome Sanger Institute, Cambridge, United Kingdom. [21] Genos Glycoscience Research Laboratory, Borongajska cesta 83H, Zagreb, Croatia.;University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia. [22] MSU Institute for Artificial Intelligence, Lomonosov Moscow State University, Moscow, Russia. yurii@bionet.nsc.ru.;Institute of Cytology and Genetics, Novosibirsk, Russia. yurii@bionet.nsc.ru. [23]
DOI 10.1038/s41467-025-60431-y
PMID 40593539
发布时间 2025-07-04
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