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Loss of CFHR5 function reduces the risk for age-related macular degeneration.

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第一作者: Mary Pat,Reeve
第一单位: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.;Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
作者单位: Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.;Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. [1] Research and Development, Biogen Inc, Cambridge, MA, USA. [2] Department of Bacteriology and Immunology, Translational Immunology Research Program, University of Helsinki, Helsinki, Finland. [3] insitro Inc., South San Francisco, CA, USA. [4] European Molecular Biological Laboratories (EMBL), Heidelberg, Germany. [5] Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.;Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. [6] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.;Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.;Division of Medical Sciences, Harvard Medical School, Boston, MA, USA. [7] Department of Bacteriology and Immunology, Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.;Department of Biomedical Sciences, Humanitas University, Milan, Italy. [8] Finnish Biobank Cooperative (FinBB), Turku, Finland. [9] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.;Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. [10] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. mjdaly@broadinstitute.org.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. mjdaly@broadinstitute.org.;Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. mjdaly@broadinstitute.org. [11] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. heiko.runz@gmail.com.;Research and Development, Biogen Inc, Cambridge, MA, USA. heiko.runz@gmail.com.;insitro Inc., South San Francisco, CA, USA. heiko.runz@gmail.com.;European Molecular Biological Laboratories (EMBL), Heidelberg, Germany. heiko.runz@gmail.com. [12]
DOI 10.1038/s41467-025-61193-3
PMID 40593839
发布时间 2025-07-08
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