Suppression of multiple mouse models of refractory malignancies by reprogramming IL-18 ligand-receptor interaction.
第一作者:
Zhen,Fan
第一单位:
Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.;Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
作者:
医学主题词
动物(Animals);小鼠(Mice);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);白细胞介素18(Interleukin-18);小鼠, 近交C57BL(Mice, Inbred C57BL);受体, 白细胞介素18(Receptors, Interleukin-18);疾病模型, 动物(Disease Models, Animal);小鼠, 近交BALB C(Mice, Inbred BALB C);溶瘤病毒(Oncolytic Viruses);肿瘤(Neoplasms);溶瘤病毒疗法(Oncolytic Virotherapy);肿瘤微环境(Tumor Microenvironment);树突细胞(Dendritic Cells);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);女(雌)性(Female);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);干扰素γ(Interferon-gamma)
DOI
10.1038/s41467-025-61439-0
PMID
40610476
发布时间
2025-07-24
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