Activatable Enzymatic Nanoplatform Incorporated into Microneedle Patch for Relieving Tumor Hypoxia Augmented Photodynamic Therapy.
第一作者:
Yashi,Li
第一单位:
Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China.;Department of Plastic and Hand Surgery, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675, Munich, Germany.
作者:
医学主题词
光化学疗法(Photochemotherapy);动物(Animals);光敏感药(Photosensitizing Agents);小鼠(Mice);过氧化氢酶(Catalase);脱植基叶绿素类(Chlorophyllides);纳米粒子(Nanoparticles);细胞系, 肿瘤(Cell Line, Tumor);卟啉类(Porphyrins);针(Needles);女(雌)性(Female);异吲哚类(Isoindoles);吲哚类(Indoles);人类(Humans);有机金属化合物(Organometallic Compounds);过氧化氢(Hydrogen Peroxide);肿瘤微环境(Tumor Microenvironment);叶绿素(Chlorophyll);锌化合物(Zinc Compounds)
DOI
10.1002/adma.202504258
PMID
40613432
发布时间
2025-10-08
基金项目
B2302047/Shenzhen Medical Research Fund
U23A2097,82372116,32301199/National Natural Science Foundation of China
(KQTD20190929172538530,JCYJ20220818095806014)/Shenzhen Science and Technology Innovation Program
BX20230235/China National Postdoctoral Program for Innovative Talents
2024M752104/China Postdoctoral Science Foundation
2023QNT017and2023QNT019/Research Team Cultivation Program of Shenzhen University
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