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USP21 deubiquitinates DPYSL2 and enhances its centrosomal abundance to promote cilium formation.

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第一作者： Ting,Song

第一单位： Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China.

作者： Ting,Song ^[1] ; Peng,Zhou ^[1] ; Fengguo,Zhang ^[2] ; Chunli,Liu ^[1] ; Xueqing,Han ^[1] ; Yiyang,Yue ^[1] ; Mingzheng,Hu ^[3] ; Shaodong,Yan ^[3] ; Qingchao,Li ^[1] ; Min,Liu ^[1] ; Jun,Zhou ^[4] ; Huijie,Zhao ^[5]

作者单位： Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China. ^[1] Medical Research and Laboratory Diagnostic Center, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250013, China. ^[2] Department of Genetics and Cell Biology, State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China. ^[3] Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China; Department of Genetics and Cell Biology, State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin 300071, China. Electronic address: junzhou@sdnu.edu.cn. ^[4] Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China. Electronic address: huijiezhao@sdnu.edu.cn. ^[5]

关键词 Cilia Ciliogenesis DPYSL2 Deubiquitination USP21