FTO-mediated m<sup>6</sup>A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.
第一作者:
Haiyang,Wang
第一单位:
Department of Laboratory Medicine, Tongji Hospital of Tongji University, School of Medicine, Tongji University, Shanghai, China.
作者:
医学主题词
肺肿瘤(Lung Neoplasms);胰岛素样生长因子结合蛋白质3(Insulin-Like Growth Factor Binding Protein 3);人类(Humans);动物(Animals);RNA结合蛋白质类(RNA-Binding Proteins);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);小鼠(Mice);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);细胞系, 肿瘤(Cell Line, Tumor)
DOI
10.1002/ctm2.70392
PMID
40621649
发布时间
2025-07-09
基金项目
82472360/National Natural Science Foundation of China
82002223/National Natural Science Foundation of China
82273417/National Natural Science Foundation of China
231107010081311/Industry-university Cooperative education program of Ministry of Education
BJWS2024074/Shanghai Oriental Talent Program top project
- 浏览0
Clinical and translational medicine
2025年15卷7期
e70392页
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