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Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization.

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第一作者： Jun,Wen

第一单位： Department of Neurology, The Frist Affiliated Hospital of Chongqing Medical University, Yuzhong District, Youyi Road, Chongqing, China.

作者： Jun,Wen ^[1] ; Hao,Tang ^[1] ; Ling,Wang ^[1] ; Qinghuan,Yang ^[1] ; Yong,Zhao ^[1] ; Yu,Ren ^[1] ; Ting,Qin ^[2] ; Xuemei,Li ^[3] ; Jianfeng,Xu ^[4] ; Gongwei,Jia ^[5] ; Qin,Yang ^[6]

作者单位： Department of Neurology, The Frist Affiliated Hospital of Chongqing Medical University, Yuzhong District, Youyi Road, Chongqing, China. ^[1] Department of Respiratory Disease, Daping Hospital, Army Medical University, Chongqing, China. ^[2] Department of Neurology, The Second People's Hospital of Chongqing Banan District, Chongqing, China. ^[3] Department of Neurosurgery, The Third People's Hospital of Mianyang, Sichuan, China. ^[4] Department of Rehabilitation, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing, 400010, China. jiagongwei@hospital.cqmu.edu.cn. ^[5] Department of Neurology, The Frist Affiliated Hospital of Chongqing Medical University, Yuzhong District, Youyi Road, Chongqing, China. xyqh200@126.com. ^[6]

关键词 ASC Ischemic stroke Osteopontin Pyroptosis Vagus nerve stimulation