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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold.

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第一作者： Muhammad Saad,Khilji

第一单位： Department of Biology, Linderstrøm-Lang Centre for Protein Science, University of Copenhagen, Copenhagen, Denmark.

作者： Muhammad Saad,Khilji ^[1] ; Celeste M,Hackney ^[1] ; Thomas L,Koch ^[2] ; Arik J,Hone ^[3] ; Aymeric,Rogalski ^[4] ; Maren,Watkins ^[5] ; Jortan,Tun ^[5] ; J Michael,McIntosh ^[6] ; Baldomero,Olivera ^[7] ; Helena,Safavi-Hemami ^[4] ; Kaare,Teilum ^[1] ; Lars,Ellgaard ^[1]

作者单位： Department of Biology, Linderstrøm-Lang Centre for Protein Science, University of Copenhagen, Copenhagen, Denmark. ^[1] Department of Biochemistry, University of Utah, Salt Lake City, Utah, United States of America.;Department of Biomedical Sciences, University of Copenhagen, Denmark. ^[2] School of Biological Sciences, University of Utah, Salt Lake City, Utah, United States of America.;MIRECC, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah, United States of America. ^[3] Department of Biochemistry, University of Utah, Salt Lake City, Utah, United States of America. ^[4] School of Biological Sciences, University of Utah, Salt Lake City, Utah, United States of America. ^[5] School of Biological Sciences, University of Utah, Salt Lake City, Utah, United States of America.;Department of Psychiatry, University of Utah, Salt Lake City, Utah, United States of America.;Mental Health Department, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah, United States of America. ^[6] Department of Biomedical Sciences, University of Copenhagen, Denmark. ^[7]

关键词 Argos EGFR signaling cone snails conotoxin protein evolution three-finger toxins venom

DOI 10.1101/2025.07.03.662903

PMID 40631153

发布时间 2025-10-13

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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold.

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Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold.

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