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Defining subgroups of pediatric nephrotic patients with urine proteomics.

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第一作者： Timothy D,Cummins

第一单位： Department of Medicine, Kidney Disease Program, University of Louisville Health Sciences Center, Room 102S Donald Baxter Research Building, Louisville, KY, 40202, USA.

作者： Timothy D,Cummins ^[1] ; Laura H,Mariani ^[2] ; Daniel W,Wilkey ^[1] ; Saeed A,Jortani ^[3] ; Margaret,Helmuth ^[2] ; Madhavi J,Rane ^[1] ; Michael L,Merchant ^[1] ; Yu,Kamigaki ^[4] ; Chandra,Theesfeld ^[5] ; Phillip J,McCown ^[2] ; Wenjun,Ju ^[2] ; Julie A,Dougherty ^[4] ; Susan,McRitchie ^[6] ; Wimal,Pathmasiri ^[6] ; Matthias,Kretzler ^[2] ; Susan J,Sumner ^[6] ; William E,Smoyer ^[7] ; Jon B,Klein ^[8] ; Cure Glomerulonephropathy (CureGN) Consortium

作者单位： Department of Medicine, Kidney Disease Program, University of Louisville Health Sciences Center, Room 102S Donald Baxter Research Building, Louisville, KY, 40202, USA. ^[1] Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA. ^[2] Department of Pathology and Lab Medicine, University of Louisville, Louisville, KY, USA. ^[3] Center for Clinical and Translational Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.;Department of Pediatrics, The Ohio State University, Columbus, OH, USA. ^[4] Genomics and Princeton Precision Health, Princeton University, Princeton, NJ, USA. ^[5] Metabolomics and Exposome Laboratory, Nutrition Research Institute, University of North Carolina, Chapel Hill, NC, USA.;Nutrition Research Institute, University of North Carolina, Chapel Hill, NC, USA. ^[6] Center for Clinical and Translational Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. William.smoyer@nationwidechildrens.org.;Department of Pediatrics, The Ohio State University, Columbus, OH, USA. William.smoyer@nationwidechildrens.org. ^[7] Department of Medicine, Kidney Disease Program, University of Louisville Health Sciences Center, Room 102S Donald Baxter Research Building, Louisville, KY, 40202, USA. Jon.klein@louisville.edu.;Robley Rex VA Medical Center, Louisville, KY, USA. Jon.klein@louisville.edu. ^[8]

关键词 FSGS MCD Nephrotic proteinuria Pediatric glomerular disease Proteomics Urine biomarker