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Sensing of extracellular ATP via P2RX7 drives lung tumor growth through regulatory T cell suppressive function.

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第一作者： Igor,Santiago-Carvalho

第一单位： Department of Immunology, Mayo Clinic, Phoenix, AZ, US.

作者： Igor,Santiago-Carvalho ^[1] ; Ronaldo,Francisco ^[2] ; Bruna,de Gois Macedo ^[1] ; Caio Loureiro,Salgado ^[1] ; Carly R,Stoll ^[1] ; Marcos Pinheiro,Cione ^[3] ; Emily,White ^[1] ; Tyler,Johnston ^[1] ; Chloe Liliana,Leff ^[1] ; Ildefonso Silva,Junior ^[1] ; Fabio Carvalho,de Souza ^[1] ; Maria Regina D'Império,Lima ^[4] ; Jessica Naomi,Lancaster ^[1] ; Henrique Borges,da Silva ^[5]

作者单位： Department of Immunology, Mayo Clinic, Phoenix, AZ, US. ^[1] Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. ^[2] Department of Immunology, Mayo Clinic, Phoenix, AZ, US.;Department of Immunology, University of Sao Paulo, Sao Paulo, SP, Brazil. ^[3] Department of Immunology, University of Sao Paulo, Sao Paulo, SP, Brazil. ^[4] Department of Immunology, Mayo Clinic, Phoenix, AZ, US.;Department of Cancer Biology, Mayo Clinic, Phoenix, AZ, US. ^[5]

DOI 10.1101/2025.05.03.652022

PMID 40654622

发布时间 2025-07-24

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Sensing of extracellular ATP via P2RX7 drives lung tumor growth through regulatory T cell suppressive function.

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Sensing of extracellular ATP via P2RX7 drives lung tumor growth through regulatory T cell suppressive function.

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