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Target trial emulation in paediatric research: how can causal effects be estimated from observational data?

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第一作者： Cal H,Robinson

第一单位： Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; SickKids Research Institute, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada. Electronic address: cal.robinson@sickkids.ca.

作者： Cal H,Robinson ^[1] ; Eddy,Fan ^[2] ; Sonia M,Grandi ^[3] ; Martin,Urner ^[4] ; Rulan S,Parekh ^[5]

作者单位： Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; SickKids Research Institute, Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada. Electronic address: cal.robinson@sickkids.ca. ^[1] Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Interdepartmental Division of Critical Care Medicine, University of Toronto, ON, Canada. ^[2] Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada; Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, ON, Canada. ^[3] Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Interdepartmental Division of Critical Care Medicine, University of Toronto, ON, Canada; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada. ^[4] Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, ON, Canada; Women's College Hospital, Department of Medicine, Toronto, ON, Canada. ^[5]

医学主题词人类(Humans);儿童(Child);儿科学(Pediatrics);研究设计(Research Design);随机对照试验(主题)(Randomized Controlled Trials as Topic);因果律(Causality);青少年(Adolescent)

DOI 10.1016/S2352-4642(25)00131-2

PMID 40659022

发布时间 2025-08-08

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The Lancet. Child & adolescent health

2025年9卷9期

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The Lancet. Child & adolescent health

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Target trial emulation in paediatric research: how can causal effects be estimated from observational data?

The Lancet. Child & adolescent health

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Target trial emulation in paediatric research: how can causal effects be estimated from observational data?

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