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The equilibrium between two quaternary assembly states determines the activity of SPOP and its cancer mutants.

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第一作者： Matthew J,Cuneo

第一单位： Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

作者： Matthew J,Cuneo ^[1] ; Ömer,Güllülü ^[1] ; Mohamed-Raafet,Ammar ^[1] ; Xinrui,Gui ^[1] ; Kelly,Churion ^[2] ; Martin,Turk ^[1] ; Brian G,O'Flynn ^[1] ; Nafiseh,Sabri ^[1] ; Tanja,Mittag ^[1]

作者单位： Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. ^[1] The Molecular Interaction Shared Resource, Proteins Technology Center, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. ^[2]

DOI 10.1101/2025.06.19.659812

PMID 40666954

发布时间 2025-07-30

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The equilibrium between two quaternary assembly states determines the activity of SPOP and its cancer mutants.

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The equilibrium between two quaternary assembly states determines the activity of SPOP and its cancer mutants.

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