Advanced Age in Mice Exacerbates Sepsis-Induced Inflammation, Vascular Permeability, and Multi-Organ Dysfunction.
第一作者:
Han Noo Ri,Lee
第一单位:
Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
作者:
关键词
ALT—alanine aminotransferaseBAL—bronchoalveolar lavageCFU—colony forming unitsCLP—cecal ligation and punctureCS—cecal slurryCXCL1—C-X-C motif chemokine ligand 1Cecal slurryGAPDH—glyceraldehyde-3-phosphate dehydrogenaseGGT—gamma-glutamyl transferaseIFN-γ—interferon gammaIL-10—interleukin-10IL-1β—interleukin-1 betaIL-6—interleukin-6KIM-1—kidney injury molecule-1LPS—lipopolysaccharideNGAL—neutrophil gelatinase associated lipocalinNIA—National Institute on AgingPBS—phosphate-buffered salineROUT—robust regression and outlier removalTNF-α—tumor necrosis factor alphaVUMC—Vanderbilt University Medical Centerage-related susceptibilityendothelial functionkidney dysfunctionkidney injurymouse modelorgan injurysystemic infection
DOI
10.1097/SHK.0000000000002657
PMID
40668087
发布时间
2026-01-31
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