首页> Clinical and experimental medicine> Single-cell RNA sequencing in human atherosclerotic plaques reveals a novel smooth muscle cell subtype that possesses multi differentiation potential and shapes the microenvironment.

Single-cell RNA sequencing in human atherosclerotic plaques reveals a novel smooth muscle cell subtype that possesses multi differentiation potential and shapes the microenvironment.

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第一作者： Weijie,Ye

第一单位： Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, China.;National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Department of Laboratory Medicine, Guangzhou First Municipal People's Hospital, The Second Affiliated Hospital of South China University of Technology, Guangzhou, Guangdong, China.

作者： Weijie,Ye ^[1] ; Zhibing,Chen ^[2] ; Zhiwei,Xia ^[3] ; Dongjie,Li ^[4]

作者单位： Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, China.;National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China.;Department of Laboratory Medicine, Guangzhou First Municipal People's Hospital, The Second Affiliated Hospital of South China University of Technology, Guangzhou, Guangdong, China. ^[1] Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[2] Department of Neurology, Hunan Aerospace Hospital, Hunan Normal University, Changsha, Hunan, China. xiazhiwei2011@gmail.com. ^[3] Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China. dongjieli@csu.edu.cn.;Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, China. dongjieli@csu.edu.cn.;National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China. dongjieli@csu.edu.cn.;Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, China. dongjieli@csu.edu.cn.;Institute of Andrology, Central South University, Changsha, Hunan, China. dongjieli@csu.edu.cn. ^[4]

关键词 Bulk RNA-seq scRNA-seq ALDOA Atherosclerosis Smooth muscle cell subtypes