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Using Metal-Organic Framework Nanoparticles for Targeted Codelivery of Bortezomib and Iron Ions to Mitochondrial TOM20 to Induce Ferroptosis for Colorectal Cancer Treatment.

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第一作者: Yao-Hua,Lu
第一单位: Shiyan Key Laboratory of Natural Medicine Nanoformulation Research, Hubei Key Laboratory of Embryonic Stem Cell Research, School of Basic Medical Sciences, Hubei University of Medicine, Renmin road No. 30, Shiyan 442000, Hubei, China.;Department of General Surgery, Taihe Hospital, Hubei University of Medicine, Renmin south road No. 32, Shiyan 442000, Hubei, China.
作者: Yao-Hua,Lu [1] ; Fan,Leng [2] ; Si-Yuan,Chen [2] ; Chen-Yu,Wang [2] ; Chang-Long,Gou [3] ; Ting-Ting,Yu [4] ; Liu-Gen,Li [2] ; Hai-Tao,Li [2] ; Min,Yan [2] ; Qiufang,Zhang [2] ; Tong-Fei,Li [2] ; Jian,Yin [5] ; Yuan-Jian,Hui [6] ; Jun,Hu [2]
作者单位: Shiyan Key Laboratory of Natural Medicine Nanoformulation Research, Hubei Key Laboratory of Embryonic Stem Cell Research, School of Basic Medical Sciences, Hubei University of Medicine, Renmin road No. 30, Shiyan 442000, Hubei, China.;Department of General Surgery, Taihe Hospital, Hubei University of Medicine, Renmin south road No. 32, Shiyan 442000, Hubei, China. [1] Shiyan Key Laboratory of Natural Medicine Nanoformulation Research, Hubei Key Laboratory of Embryonic Stem Cell Research, School of Basic Medical Sciences, Hubei University of Medicine, Renmin road No. 30, Shiyan 442000, Hubei, China. [2] Department of Ultrasound Medicine, Taihe Hospital, Hubei University of Medicine, Renmin south road No. 32, Shiyan 442000, Hubei, China. [3] Department of Pathology, Renmin Hospital of Shiyan, Hubei University of Medicine, Shiyan 442000, Hubei, China. [4] School of Biotechnology, Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Innovation Center for Vaccine Engineering, Jiangnan University, Wuxi 214122, China. [5] Department of General Surgery, Taihe Hospital, Hubei University of Medicine, Renmin south road No. 32, Shiyan 442000, Hubei, China. [6]
DOI 10.1021/acs.molpharmaceut.5c00489
PMID 40671590
发布时间 2025-08-04
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Molecular pharmaceutics

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