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Donidalorsen Treatment of Hereditary Angioedema in Patients Previously on Long-Term Prophylaxis.

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第一作者： Marc A,Riedl

第一单位： Division of Allergy and Immunology, University of California San Diego, La Jolla, Calif.

作者： Marc A,Riedl ^[1] ; Jonathan A,Bernstein ^[2] ; Joshua S,Jacobs ^[3] ; Timothy,Craig ^[4] ; Aleena,Banerji ^[5] ; Francesca,Perego ^[6] ; William R,Lumry ^[7] ; H James,Wedner ^[8] ; Selina,Gierer ^[9] ; Michael E,Manning ^[10] ; Laura,Bordone ^[11] ; Sabrina,Treadwell ^[11] ; Tao,Lin ^[11] ; Kenneth B,Newman ^[11] ; Aaron,Yarlas ^[11] ; Danny M,Cohn ^[12]

作者单位： Division of Allergy and Immunology, University of California San Diego, La Jolla, Calif. ^[1] Division of Rheumatology, Allergy, and Immunology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio; Bernstein Clinical Research Center, LLC, Cincinnati, Ohio. ^[2] Allergy and Asthma Clinical Research, Inc., Walnut Creek, Calif. ^[3] Department of Medicine, Pediatrics, and Biomedical Sciences, Penn State Health Allergy, Asthma, and Immunology, Hershey, Pa; Department of General Internal Medicine, Vinmec International Hospital, Times City, Hanoi, Vietnam. ^[4] Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass. ^[5] Department of Internal Medicine, Istituto di Ricovero e Cura a Carattere Scientifico, Istituti Clinici Scientifici Maugeri, Milan, Italy. ^[6] Asthma and Allergy Research Associates, Dallas, Texas. ^[7] Division of Allergy and Immunology, Washington University, St Louis, Mo. ^[8] Division of Allergy, Clinical Immunology, and Rheumatology, University of Kansas Medical Center, Kansas City, Kan. ^[9] Medical Research of Arizona, Scottsdale, Ariz. ^[10] Ionis, Carlsbad, Calif. ^[11] Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: d.m.cohn@amsterdamumc.nl. ^[12]

关键词 Disease control Donidalorsen Hereditary angioedema Open-label Phase 3 Treatment preference

医学主题词人类(Humans);血管水肿, 遗传性(Angioedemas, Hereditary);男(雄)性(Male);女(雌)性(Female);中年人(Middle Aged);成年人(Adult);生活质量(Quality of Life);寡核苷酸类, 反义(Oligonucleotides, Antisense);老年人(Aged);治疗结果(Treatment Outcome);补体C1抑制蛋白质(Complement C1 Inhibitor Protein);青年人(Young Adult);寡核苷酸类(Oligonucleotides)

DOI 10.1016/j.jaip.2025.06.018

PMID 40673861

发布时间 2025-09-22

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The journal of allergy and clinical immunology. In practice

2025年13卷9期

2381-2389.e3页

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The journal of allergy and clinical immunology. In practice

2025年13卷9期

2381-2389.e3页

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Donidalorsen Treatment of Hereditary Angioedema in Patients Previously on Long-Term Prophylaxis.

The journal of allergy and clinical immunology. In practice

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Donidalorsen Treatment of Hereditary Angioedema in Patients Previously on Long-Term Prophylaxis.

The journal of allergy and clinical immunology. In practice

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The journal of allergy and clinical immunology. In practice

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