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BRD2 Bromodomain-Mediated Regulation of Cell State Plasticity Modulates Therapy Response in Glioblastoma.

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第一作者： Raghavendra,Vadla

第一单位： Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

作者： Raghavendra,Vadla ^[1] ; Brett,Taylor ^[2] ; Yohei,Miyake ^[1] ; Benjamin,Lin ^[3] ; Daisuke,Kawauchi ^[1] ; Shunichiro,Miki ^[1] ; Nidhi,Nathwani ^[1] ; Brandon M,Jones ^[1] ; Yashpreet,Kaur ^[1] ; Abhinaba,Banerjee ^[4] ; Philip,Pham ^[1] ; Jonathan,Tsang ^[5] ; Albert,Baldwin ^[6] ; David A,Nathanson ^[4] ; Donald P,Pizzo ^[7] ; C Ryan,Miller ^[8] ; Frank B,Furnari ^[1]

作者单位： Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA. ^[1] Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.;Medical Scientist Training Program, University of California, San Diego, La Jolla, CA 92093, USA. ^[2] Department of Pathology, Division of Neuropathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.;Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[3] Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA. ^[4] Departments of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA. ^[5] UNC Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA. ^[6] Department of Pathology, University of California San Diego, La Jolla, CA 92093, USA. ^[7] Department of Pathology, Division of Neuropathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[8]

关键词 BET inhibitors BRD2 Glioblastoma Mesenchymal NF-κB signaling

DOI 10.1093/neuonc/noaf169

PMID 40686478

发布时间 2025-12-14

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