M2 macrophage-derived Apolipoprotein E promotes fibroblast MMPs expression via LRP1-ERK signaling in chronic rhinosinusitis with nasal polyps.-论文-万方医学网

第一作者： Ying,Zhu

第一单位： Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Otolaryngological Institute, Shanghai Jiao Tong University, Shanghai, PR China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, PR China.

作者： Ying,Zhu ^[1] ; Jiayao,Zhou ^[1] ; Ru,Tang ^[1] ; Shiyao,Zhang ^[1] ; Chunyu,Luo ^[1] ; Yuelong,Gu ^[1] ; Shilei,Pu ^[2] ; Song,Mao ^[1] ; Hai,Lin ^[1] ; Haibo,Ye ^[3] ; Zhipeng,Li ^[4] ; Weitian,Zhang ^[5]

作者单位： Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Otolaryngological Institute, Shanghai Jiao Tong University, Shanghai, PR China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, PR China. ^[1] Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Otolaryngological Institute, Shanghai Jiao Tong University, Shanghai, PR China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, PR China; Department of Otolaryngology-Head and Neck Surgery, Shanghai Children's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. ^[2] Department of Otolaryngology-Head and Neck Surgery, Shanghai Tenth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, PR China. ^[3] Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Otolaryngological Institute, Shanghai Jiao Tong University, Shanghai, PR China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, PR China. Electronic address: lizhipeng_ent@163.com. ^[4] Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Otolaryngological Institute, Shanghai Jiao Tong University, Shanghai, PR China; Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, PR China. Electronic address: drzhangwt@163.com. ^[5]

医学主题词人类(Humans);鼻息肉(Nasal Polyps);鼻窦炎(Sinusitis);动物(Animals);巨噬细胞(Macrophages);鼻炎(Rhinitis);小鼠(Mice);慢性病(Chronic Disease);载脂蛋白E类(Apolipoproteins E);成纤维细胞(Fibroblasts);男(雄)性(Male);女(雌)性(Female);基质金属蛋白酶类(Matrix Metalloproteinases);小鼠, 基因敲除(Mice, Knockout);疾病模型, 动物(Disease Models, Animal);基质金属蛋白酶9(Matrix Metalloproteinase 9);MAP激酶信号系统(MAP Kinase Signaling System);细胞, 培养的(Cells, Cultured);成年人(Adult);信号传导(Signal Transduction);中年人(Middle Aged)

DOI 10.1016/j.mucimm.2025.07.004

PMID 40691969

发布时间 2025-10-10

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M2 macrophage-derived Apolipoprotein E promotes fibroblast MMPs expression via LRP1-ERK signaling in chronic rhinosinusitis with nasal polyps.

Mucosal immunology

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Mucosal immunology

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M2 macrophage-derived Apolipoprotein E promotes fibroblast MMPs expression via LRP1-ERK signaling in chronic rhinosinusitis with nasal polyps.

Mucosal immunology

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同项目论文

Mucosal immunology

相关期刊

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