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Subgroup-based model selection to improve the prediction of vancomycin concentrations.

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第一作者： Hanna Kadri,Laas

第一单位： Department of Microbiology, University of Tartu, Tartu, Estonia.;Anaesthesiology and Intensive Care Clinic, Tartu University Hospital, Tartu, Estonia.

作者： Hanna Kadri,Laas ^[1] ; Tuuli,Metsvaht ^[2] ; Kadri,Tamme ^[3] ; Juri,Karjagin ^[3] ; Kristiina,Naber ^[4] ; Artjom,Afanasjev ^[4] ; Carmen,Tiivel ^[4] ; Irja,Lutsar ^[4] ; Hiie,Soeorg ^[1]

作者单位： Department of Microbiology, University of Tartu, Tartu, Estonia.;Anaesthesiology and Intensive Care Clinic, Tartu University Hospital, Tartu, Estonia. ^[1] Department of Microbiology, University of Tartu, Tartu, Estonia.;Children's Clinic, Tartu University Hospital, Tartu, Estonia.;Department of Paediatrics, University of Tartu, Tartu, Estonia. ^[2] Anaesthesiology and Intensive Care Clinic, Tartu University Hospital, Tartu, Estonia.;Department of Anaesthesiology and Intensive Care, University of Tartu, Tartu, Estonia. ^[3] Department of Microbiology, University of Tartu, Tartu, Estonia. ^[4]

关键词 critically ill patients decision algorithm decision tree external evaluation genetic algorithm individualized dosing intensive care unit patients model selection model-informed precision dosing