首页> Systematic reviews> Is noxious stimulus-evoked electroencephalography response a reliable, valid, and interpretable outcome measure to assess analgesic efficacy in neonates? A systematic review and individual participant data (IPD) meta-analysis protocol.

Is noxious stimulus-evoked electroencephalography response a reliable, valid, and interpretable outcome measure to assess analgesic efficacy in neonates? A systematic review and individual participant data (IPD) meta-analysis protocol.

导出 OA

翻译打印收藏纠错

第一作者： Luke,Baxter

第一单位： Department of Paediatrics, University of Oxford, Oxford, UK. luke.baxter@paediatrics.ox.ac.uk.;Paediatric Neuroimaging Group Level2 Childrens Hospital, John Radcliffe Hospital, Oxford, UK. luke.baxter@paediatrics.ox.ac.uk.

作者： Luke,Baxter ^[1] ; Marianne,van der Vaart ^[2] ; Maria M,Cobo ^[3] ; Patricia Y,Gunawan ^[4] ; Karel,Allegaert ^[5] ; Jonathan M,Davis ^[6] ; Mark,Turner ^[7] ; Robert M,Ward ^[8] ; Edress,Darsey ^[9] ; James P,Sheppard ^[10] ; Aomesh,Bhatt ^[2] ; John,van den Anker ^[11] ; An N,Massaro ^[12] ; Ramona L,Walls ^[13] ; Laura S,Song ^[13] ; Kanwaljit,Singh ^[14] ; INC Pain Working Group ^[2] ; Rebeccah,Slater

作者单位： Department of Paediatrics, University of Oxford, Oxford, UK. luke.baxter@paediatrics.ox.ac.uk.;Paediatric Neuroimaging Group Level2 Childrens Hospital, John Radcliffe Hospital, Oxford, UK. luke.baxter@paediatrics.ox.ac.uk. ^[1] Department of Paediatrics, University of Oxford, Oxford, UK. ^[2] Department of Paediatrics, University of Oxford, Oxford, UK.;Colegio de Ciencias Biologicas y Ambientales, Universidad San Francisco de Quito USFQ, Quito, Ecuador. ^[3] Department of Paediatrics, University of Oxford, Oxford, UK.;Department of Child Health, Universitas Pelita Harapan, Tangerang, Indonesia. ^[4] Department of Development and Regeneration, KU Leuven, Leuven, Belgium.;Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.;Department of Hospital Pharmacy, Erasmus Medical Center, Rotterdam, the Netherlands. ^[5] Department of Pediatrics, Tufts Medical Center, Boston, MA, USA. ^[6] Department of Womens and Childrens Health, University of Liverpool, Liverpool, UK. ^[7] Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA. ^[8] Pediatric Center of Excellence, Pfizer, NY, USA. ^[9] Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. ^[10] Department of Paediatrics, University of Oxford, Oxford, UK.;Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA. ^[11] Office of Pediatric Therapeutics, Food and Drug Administration (FDA), Silver Spring, MD, USA. ^[12] Critical Path Institute, Data Collaboration Center, Tucson, AZ, USA. ^[13] INC, Critical Path Institute (C-Path), Tucson, AZ, USA. ^[14]

关键词 Biomarkers Brain Electroencephalography Individual participant data Interpretability Meta-analysis Neonate Pain Reliability Validity

医学主题词人类(Humans);脑电描记术(Electroencephalography);婴儿, 新生(Infant, Newborn);Meta分析(主题)(Meta-Analysis as Topic);结果可重复性(Reproducibility of Results);疼痛测定(Pain Measurement);镇痛药(Analgesics)

DOI 10.1186/s13643-025-02890-4

PMID 40713869

发布时间 2025-07-31

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交