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Combating biofilm formation and bacterial killing: N-acetylcysteine's efficacy against <i>Pseudomonas aeruginosa</i> in urinary catheters.

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第一作者： Arthika,Manoharan

第一单位： Infection, Immunity and Inflammation Theme, School of Medical Sciences, Charles Perkins Centre, The University of Sydney, Sydney, Australia.;Sydney Infectious Diseases Institute, The University of Sydney, Sydney, Australia.

作者： Arthika,Manoharan ^[1] ; Greg,Whiteley ^[2] ; Rajesh,Kuppusamy ^[3] ; Slade,Jensen ^[4] ; Trevor,Glasbey ^[5] ; Zhuoran,Chen ^[6] ; Lia,Moshkanbaryans ^[3] ; Kate H,Moore ^[6] ; Theerthankar,Das ^[7] ; Jim,Manos ^[1]

作者单位： Infection, Immunity and Inflammation Theme, School of Medical Sciences, Charles Perkins Centre, The University of Sydney, Sydney, Australia.;Sydney Infectious Diseases Institute, The University of Sydney, Sydney, Australia. ^[1] Infection, Immunity and Inflammation Theme, School of Medical Sciences, Charles Perkins Centre, The University of Sydney, Sydney, Australia.;Sydney Infectious Diseases Institute, The University of Sydney, Sydney, Australia.;Whiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW, 2319, Australia. ^[2] Infection, Immunity and Inflammation Theme, School of Medical Sciences, Charles Perkins Centre, The University of Sydney, Sydney, Australia.;Whiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW, 2319, Australia. ^[3] Microbiology and Infectious Diseases, School of Medicine, Ingham Institute, Western Sydney University, NSW, Australia. ^[4] Whiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW, 2319, Australia. ^[5] Department of Urogynaecology, St George Hospital, University of New South Wales, Sydney, NSW, 2052, Australia. ^[6] Infection, Immunity and Inflammation Theme, School of Medical Sciences, Charles Perkins Centre, The University of Sydney, Sydney, Australia.;Sydney Infectious Diseases Institute, The University of Sydney, Sydney, Australia.;Microbiology and Infectious Diseases, School of Medicine, Ingham Institute, Western Sydney University, NSW, Australia. ^[7]

关键词 Biofilm Bladder CA-UTI Catheter blockage Catheter-associated UTIs Infection NAC Pseudomonas aeruginosa

DOI 10.1016/j.bioflm.2025.100296

PMID 40726828

发布时间 2025-07-31

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Combating biofilm formation and bacterial killing: N-acetylcysteine's efficacy against <i>Pseudomonas aeruginosa</i> in urinary catheters.

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Combating biofilm formation and bacterial killing: N-acetylcysteine's efficacy against <i>Pseudomonas aeruginosa</i> in urinary catheters.

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