换一批Nodosin alleviates cholestatic liver injury by activation of SIRT1/FXR signaling pathway and inhibition of hepatic inflammation.
第一作者：
Mingzhu,Han
第一单位：
State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Bioactive Natural Product Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
作者：
医学主题词
溪黄草属(Isodon);二萜类(Diterpenes);胆汁淤积, 肝内(Cholestasis, Intrahepatic);植物提取物(Plant Extracts);小鼠, 近交C57BL(Mice, Inbred C57BL);Hep G2细胞(Hep G2 Cells);人类(Humans);男(雄)性(Male);动物(Animals);小鼠(Mice);胆固醇7-α-羟化酶(Cholesterol 7-alpha-Hydroxylase);抗衰老酶1(Sirtuin 1);NF-κB(NF-kappa B);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear)
DOI
10.1016/j.bcp.2025.117200
PMID
40749957
发布时间
2025-11-28
- 浏览1
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
