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Advancing Genotoxicity Assessment by Building a Global AOP Network.

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第一作者： E,Demuynck

第一单位： Scientific Direction of Chemical and Physical Health Risks, Sciensano, Brussels, Belgium.;Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Brussels, Belgium.

作者： E,Demuynck ^[1] ; T,Vanhaecke ^[2] ; A,Thienpont ^[3] ; D,Cappoen ^[3] ; F,Van Goethem ^[2] ; L M T,Winkelman ^[4] ; J B,Beltman ^[4] ; S,Murugadoss ^[5] ; A-K,Olsen ^[5] ; F,Marcon ^[6] ; C,Bossa ^[6] ; S M,Shaikh ^[7] ; D,Nikolopoulou ^[8] ; V,Hatzi ^[8] ; J,Pennings ^[9] ; M,Luijten ^[9] ; C,Adam-Guillermin ^[10] ; M,Paparella ^[11] ; M,Audebert ^[12] ; B,Mertens ^[3]

作者单位： Scientific Direction of Chemical and Physical Health Risks, Sciensano, Brussels, Belgium.;Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Brussels, Belgium. ^[1] Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Brussels, Belgium. ^[2] Scientific Direction of Chemical and Physical Health Risks, Sciensano, Brussels, Belgium. ^[3] Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands. ^[4] The Health Effects Laboratory, Department for Environmental Chemistry and Health Effects, The Climate and Environment Institute NILU, Kjeller, Norway. ^[5] Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy. ^[6] KWR Water Research Institute, Nieuwegein, the Netherlands. ^[7] Laboratory of Toxicological Control of Pesticides, Benaki Phytopathological Institute, Athens, Greece. ^[8] Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. ^[9] PSE Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Fontenay-aux-Roses, France. ^[10] Institute for Medical Biochemistry, Medical University Innsbruck, Innsbruck, Austria. ^[11] Toxalim UMR1331, Toulouse University, INRAE, Toulouse, France. ^[12]

关键词 AOP IATA NAMs genotoxicity

医学主题词动物(Animals);人类(Humans);动物替代试验(Animal Testing Alternatives);DNA损伤(DNA Damage);诱变力试验(Mutagenicity Tests);诱变剂(Mutagens);危险性评估(Risk Assessment)

DOI 10.1002/em.70022

PMID 40785417

发布时间 2026-06-10

基金项目

::The European Partnership for the Assessment of Risks from Chemicals (PARC):: 101057014/European Union's Horizon Europe Research and Innovation Programme

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交