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Energy Deficiency-Induced ATG4B Nuclear Translocation Inhibits PRMT1-Mediated DNA Repair and Promotes Leukemia Progression.

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第一作者： Zhenkun,Wang

第一单位： Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.

作者： Zhenkun,Wang ^[1] ; Xianli,Zhang ^[1] ; Yuanyuan,Zhou ^[2] ; Shuyi,Lin ^[1] ; Yuting,Fu ^[1] ; Haiping,Liu ^[1] ; Qiongdan,Gao ^[1] ; YanHong,Xiao ^[3] ; Zhao,Yin ^[4] ; Shuang,Liu ^[4] ; Kexiu,Huang ^[5] ; Suqi,Deng ^[5] ; Juan,Du ^[5] ; Hui,Zeng ^[5] ; Jia,Wang ^[6] ; Jinping,Zheng ^[6] ; Qinghua,Zhou ^[7] ; Tianfeng,Chen ^[8] ; Xiaoling,Gao ^[9] ; Zhenyu,Ju ^[1] ; Bo,Liu ^[1]

作者单位： Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. ^[1] Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.;Shanxi Key Laboratory of Aging Mechanism Research and Translational Applications, Changzhi Medical College, Changzhi, Shanxi, 046000, China. ^[2] Biomedical Innovation Center, Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. ^[3] Guangdong Second Provincial General Hospital, Jinan university, Guangzhou, 510317, China. ^[4] Department of Hematology, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. ^[5] Shanxi Key Laboratory of Aging Mechanism Research and Translational Applications, Changzhi Medical College, Changzhi, Shanxi, 046000, China. ^[6] College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. ^[7] Department of Chemistry, Jinan University, Guangzhou, 510632, China. ^[8] The clinical Laboratory Center, Hainan General Hospital, Hainan affiliated Hospital of Hainan Medical University, Haikou, 570311, China. ^[9]

关键词 ATG4B DNA repair Energy metabolism Leukemia PRMT1