首页> European journal of heart failure> A multicentre, randomized, double-blind, active and placebo-controlled study of pecavaptan, a dual V1a/V2 vasopressin receptor antagonist, in patients with acute heart failure: The AVANTI trial.

A multicentre, randomized, double-blind, active and placebo-controlled study of pecavaptan, a dual V1a/V2 vasopressin receptor antagonist, in patients with acute heart failure: The AVANTI trial.

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第一作者： James E,Udelson

第一单位： Division of Cardiology and the CardioVascular Centre, Tufts Medical Center, Boston, MA, USA.

作者： James E,Udelson ^[1] ; Steven R,Goldsmith ^[2] ; Daniel,Burkhoff ^[3] ; Pablo,Colorado ^[4] ; Wilfried,Dinh ^[5] ; Finn,Gustafsson ^[6] ; Peter,Kolkhof ^[7] ; Gerald,Staedtler ^[8] ; Iouri,Bachmakov ^[9] ; Adriaan A,Voors ^[10] ; Kevin,Duarte ^[11] ; Luca,Monzo ^[11] ; Nicolas,Girerd ^[11] ; Faiez,Zannad ^[11]

作者单位： Division of Cardiology and the CardioVascular Centre, Tufts Medical Center, Boston, MA, USA. ^[1] Hennepin County Medical Center, University of Minnesota, Minneapolis, MN, USA. ^[2] Cardiovascular Research Foundation, New York, NY, USA. ^[3] Bayer US LLC Pharmaceuticals, Whippany, NJ, USA. ^[4] Bayer AG, Research and Development, Pharmaceuticals, Translational Sciences, Translational Clinical Medicine, Experimental Medicine 1, Wuppertal, Germany and the Centre for Clinical Medicine, University Faculty of Health, University of Witten Herdecke, Witten, Germany. ^[5] Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. ^[6] Bayer AG, Research and Early Development, Cardiovascular Precision Medicines, Wuppertal, Germany. ^[7] Bayer AG, Research and Development, Pharmaceuticals, TA Statistics 1 CNTH, Berlin, Germany. ^[8] Bayer AG, Medical Affairs & Pharmacovigilance, Pharmaceuticals, Pharmacovigilance-Benefit Risk Management, Cardiorenal Development, Wuppertal, Germany. ^[9] Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands. ^[10] INSERM, Centre d'Investigations Cliniques Plurithématique 1433, Inserm U1116, CHRU de Nancy, F-CRIN INI-CR, Université de Lorraine, Nancy, France. ^[11]

关键词 Decongestion Diuretic Heart failure Vasopressin