Inhibition of calcium-sensing receptor by its antagonist protects dopaminergic neurons from MPTP/MPP<sup>+</sup>-induced neurotoxicity via regulating mitochondrial function, autophagy, and apoptosis in vivo and in vitro.
第一作者:
Huiping,Qi
第一单位:
Department of Neurology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
作者:
医学主题词
动物(Animals);受体, 钙敏感(Receptors, Calcium-Sensing);自噬(Autophagy);细胞凋亡(Apoptosis);线粒体(Mitochondria);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);男(雄)性(Male);神经保护药(Neuroprotective Agents);1-甲基-4-苯基吡啶(1-Methyl-4-phenylpyridinium)
DOI
10.1016/j.neulet.2025.138351
PMID
40789434
发布时间
2025-10-03
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Neuroscience letters
138351页
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