miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
第一作者:
Wen,Pan
第一单位:
Department of Health Management Center, The Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Ximianqiao Street No.20, Chengdu, 610041, Sichuan, China.
作者:
医学主题词
微RNAs(MicroRNAs);人类(Humans);胃肿瘤(Stomach Neoplasms);糖酵解(Glycolysis);rab GTP结合蛋白质类(rab GTP-Binding Proteins);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);细胞运动(Cell Movement);细胞系, 肿瘤(Cell Line, Tumor);信号传导(Signal Transduction);动物(Animals);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);肿瘤侵润(Neoplasm Invasiveness);小鼠(Mice);上皮-间质转化(Epithelial-Mesenchymal Transition);基因, 肿瘤抑制(Genes, Tumor Suppressor);小鼠, 裸(Mice, Nude)
DOI
10.1038/s41598-025-02139-z
PMID
40796564
发布时间
2025-08-26
基金项目
XZ202301YD0031C/Local projects based on central guidance of China
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