首页> Nature communications> Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling.

Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling.

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第一作者： Cristiana C,Santos

第一单位： Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.

作者： Cristiana C,Santos ^[1] ; Nadine,Schweizer ^[1] ; Fátima,Cairrão ^[1] ; Juanma,Ramirez ^[2] ; Nerea,Osinalde ^[2] ; Ming,Yang ^[3] ; Catarina J,Gaspar ^[4] ; Vanya I,Rasheva ^[1] ; Miguel L,Trigo ^[1] ; Zach,Hensel ^[1] ; Colin,Adrain ^[5] ; Tiago N,Cordeiro ^[1] ; Franka,Voigt ^[3] ; Paulo A,Gameiro ^[6] ; Ugo,Mayor ^[7] ; Pedro M,Domingos ^[8]

作者单位： Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal. ^[1] Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain. ^[2] Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland. ^[3] Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.;Department of Research Oncology, Genentech, Inc. 1 DNA Way, South San Francisco, CA, USA. ^[4] Patrick G Johnston Centre for Cancer Research, Queen's University, Belfast, UK. ^[5] NOVA Medical School Faculdade de Ciências Médicas, NMS FCM, Universidade Nova de Lisboa, Lisboa, Portugal. ^[6] Department of Biochemistry and Molecular Biology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.;Ikerbasque, Basque Foundation for Science, Bilbao, Spain. ^[7] Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal. domingp@itqb.unl.pt. ^[8]