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Drift Parameter Based Sample Size Determination in Multi-Stage Bayesian Randomized Clinical Trials.

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第一作者： Yueyang,Han

第一单位： Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, British Columbia, Canada.

作者： Yueyang,Han ^[1] ; Haolun,Shi ^[1] ; Jiguo,Cao ^[1] ; Ruitao,Lin ^[2]

作者单位： Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, British Columbia, Canada. ^[1] Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[2]

关键词 Bayesian design multi‐stage design phase II clinical trial posterior probability randomized trial sample size

医学主题词贝叶斯定理(Bayes Theorem);人类(Humans);随机对照试验(主题)(Randomized Controlled Trials as Topic);样本大小(Sample Size);临床试验, Ⅱ期(主题)(Clinical Trials, Phase II as Topic);研究设计(Research Design);算法(Algorithms);模型, 统计学(Models, Statistical);线性模型(Linear Models)

DOI 10.1002/pst.70037

PMID 40810309

发布时间 2025-08-26

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