首页> BMC medicine> Basophil-derived exosomes exacerbate systemic lupus erythematosus by regulating B-cell proliferation via miR-24550.

Basophil-derived exosomes exacerbate systemic lupus erythematosus by regulating B-cell proliferation via miR-24550.

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第一作者： Jiaxuan,Chen

第一单位： Department of Nephrology, National Clinical Key Specialty Construction Program, Institute of Nephrology, Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524000, China.

作者： Jiaxuan,Chen ^[1] ; Shuzhen,Liao ^[1] ; Jiaqi,Lun ^[1] ; Xing,Lu ^[1] ; Bitang,Huang ^[1] ; Xiaoxian,Liu ^[1] ; Xiaowei,Xu ^[1] ; Lawei,Yang ^[1] ; Fengbiao,Guo ^[1] ; Liuyong,You ^[2] ; Haiyan,Xiao ^[3] ; Hua-Feng,Liu ^[4] ; Qingjun,Pan ^[5]

作者单位： Department of Nephrology, National Clinical Key Specialty Construction Program, Institute of Nephrology, Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524000, China. ^[1] Department of Clinical Laboratory, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. ^[2] Department of Cellular Biology and Anatomy, James and Jean Culver Vision Discovery Institute, Medical College of Georgia, Augusta University, Augusta, 30912, USA. ^[3] Department of Nephrology, National Clinical Key Specialty Construction Program, Institute of Nephrology, Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524000, China. liuhf@gdmu.edu.cn. ^[4] Department of Nephrology, National Clinical Key Specialty Construction Program, Institute of Nephrology, Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524000, China. stillwater2004@126.com.;Department of Clinical Laboratory, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. stillwater2004@126.com. ^[5]

关键词 B cells Basophils Exosomes Systemic lupus erythematosus miR-24550