首页> Journal for immunotherapy of cancer> Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer.

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer.

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第一作者： Hui,Yu

第一单位： Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Uppsala County, Sweden.

作者： Hui,Yu ^[1] ; Anastasia,Magoulopoulou ^[2] ; Rose-Marie,Amini ^[1] ; Maria Paraskevi,Chatzinikolaou ^[2] ; Masafumi,Horie ^[3] ; Amanda,Lindberg ^[1] ; Artur,Mezheyeuski ^[4] ; Max,Backman ^[1] ; Andreas,Metousis ^[5] ; Hans,Brunnström ^[6] ; Millaray,Marincevic ^[1] ; Johan,Botling ^[1] ; Johanna Sofia Margareta,Mattsson ^[1] ; Klas,Kärre ^[7] ; Karin,Leandersson ^[8] ; Mats,Nilsson ^[2] ; Carina,Strell ^[9] ; Patrick,Micke ^[10]

作者单位： Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Uppsala County, Sweden. ^[1] Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Stockholm County, Sweden. ^[2] Division of Molecular and Genomic Pathology, Department of Pathology, Kobe University Graduate School of Medicine, Kobe, Japan. ^[3] Molecular Oncology Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain. ^[4] Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Stockholm County, Sweden.;Dept. of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany. ^[5] Division of Pathology, Lund University, Lund, Sweden. ^[6] Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Stockholm County, Sweden. ^[7] Department of Translational Medicine, Lund University, Lund, Sweden. ^[8] Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Uppsala County, Sweden patrick.micke@igp.uu.se carina.strell@igp.uu.se.;Center for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen, Bergen, Norway. ^[9] Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Uppsala County, Sweden patrick.micke@igp.uu.se carina.strell@igp.uu.se. ^[10]

关键词 Clonality Immune Checkpoint Inhibitor Lung Cancer T cell T cell Receptor - TCR