首页> International journal for parasitology. Drugs and drug resistance> In vitro screening of the open-access Pandemic Response Box reveals ESI-09 as a compound with activity against Echinococcus multilocularis.

In vitro screening of the open-access Pandemic Response Box reveals ESI-09 as a compound with activity against Echinococcus multilocularis.

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第一作者： Pascal,Zumstein

第一单位： Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.

作者： Pascal,Zumstein ^[1] ; Anissa,Bartetzko ^[2] ; Marc,Kaethner ^[2] ; Laura,Vetter ^[2] ; Andrew,Hemphill ^[2] ; Trix,Zumkehr ^[2] ; Benoît,Laleu ^[3] ; Matías,Preza ^[4] ; Britta,Lundström-Stadelmann ^[5]

作者单位： Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland. ^[1] Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. ^[2] MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland. ^[3] Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland. Electronic address: matias.preza@unibe.ch. ^[4] Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Multidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland. Electronic address: britta.lundstroem@unibe.ch. ^[5]

关键词 Alveolar echinococcosis DNDi Drug repurposing Echinococcus mutlilocularis MMV Mitochondrial uncoupler

医学主题词多房棘球绦虫(Echinococcus multilocularis);动物(Animals);药物重新定位(Drug Repositioning);人类(Humans);抗蠕虫药(Anthelmintics);药物评价, 临床前(Drug Evaluation, Preclinical);棘球蚴病(Echinococcosis)

DOI 10.1016/j.ijpddr.2025.100609

PMID 40876356

发布时间 2025-12-17

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