首页> Clinical immunology (Orlando, Fla.)> Identification of immune complex antigens that are detected prior to early rheumatoid arthritis symptoms and increase with disease progression: Comprehensive serum immune complexome analysis to identify candidate disease biomarkers in health checkup cohort study.

Identification of immune complex antigens that are detected prior to early rheumatoid arthritis symptoms and increase with disease progression: Comprehensive serum immune complexome analysis to identify candidate disease biomarkers in health checkup cohort study.

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第一作者： Yuki Jimbayashi,Kutsuna

第一单位： Department of Molecular Pathochemistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Department of Pharmacy Practice, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

作者： Yuki Jimbayashi,Kutsuna ^[1] ; Nozomi,Aibara ^[2] ; Junya,Hashizume ^[3] ; Sayaka,Kawarabayashi ^[4] ; Mami,Tamai ^[5] ; Jun,Miyata ^[6] ; Hajime,Yoshifuji ^[7] ; Hirotaka,Miyamoto ^[8] ; Kayoko,Sato ^[3] ; Yukinobu,Kodama ^[9] ; Mikiro,Nakashima ^[2] ; Atsushi,Kawakami ^[5] ; Takahiro,Maeda ^[10] ; Kaname,Ohyama ^[11]

作者单位： Department of Molecular Pathochemistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Department of Pharmacy Practice, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. ^[1] Department of Pharmacy Practice, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. ^[2] Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan. ^[3] School of Pharmacy, Nagasaki University, Nagasaki, Japan. ^[4] Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Leading Medical Research Core Unit, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. ^[5] Leading Medical Research Core Unit, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Department of Island and Community Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. ^[6] Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[7] Department of Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan. ^[8] Department of Molecular Pathochemistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan. ^[9] Leading Medical Research Core Unit, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Department of Island and Community Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. ^[10] Department of Molecular Pathochemistry, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan; Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan. Electronic address: k-ohyama@nagasaki-u.ac.jp. ^[11]

关键词 Immune complexes Immune complexome analysis Janus kinase and microtubule-interacting protein 3 Peroxisome proliferator-activated receptor gamma coactivator 1-beta Protein-glutamine gamma-glutamyltransferase E Rheumatoid arthritis