首页> Bioanalysis> Pharmacokinetic-pharmacodynamic and tissue distribution studies in physiological and cerebral ischemia-reperfusion injury rats after oral administration of anisodine hydrobromide tablets.

Pharmacokinetic-pharmacodynamic and tissue distribution studies in physiological and cerebral ischemia-reperfusion injury rats after oral administration of anisodine hydrobromide tablets.

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第一作者： Yujie,Yu

第一单位： State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

作者： Yujie,Yu ^[1] ; Yanfang,Liu ^[1] ; Jianlan,Zhang ^[1] ; Shu,Dai ^[1] ; Rui,Wu ^[1] ; Feng,Wan ^[2] ; Chenhao,Yao ^[1] ; Yuxin,Yao ^[1] ; Feng,Nan ^[3] ; Yunxia,Li ^[1]

作者单位： State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China. ^[1] State Key Laboratory of Southwestern Chinese Medicine Resources, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.;Chengdu NO. 1 Pharmaceutical Co. Ltd, Pengzhou, Sichuan, China. ^[2] The Department of National Drug Clinical Trial Agency, The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China. ^[3]

关键词 Anisodine hydrobromide UPLC-MS/MS cerebral ischemia-reperfusion injury neuroprotective effect pharmacokinetic-pharmacodynamic combined model pharmacokinetics tissue distribution