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Tumor-activated nanocomplex reprograms cancer and macrophage metabolism in opposite directions to overcome immune suppression.

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第一作者： Zan,Dai

第一单位： Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia; Children's Cancer Institute, School of Medicine and Health, UNSW Sydney, Sydney, 2052, Australia. Electronic address: zan.dai@unsw.edu.au.

作者： Zan,Dai ^[1] ; Qiaoyun,Wang ^[2] ; Ming,Zhang ^[3] ; Yiru,Shi ^[4] ; Yannan,Yang ^[4] ; Hao,Song ^[5] ; Runming,Wang ^[6] ; Bernt,Johannessen ^[7] ; Xu,Zhen ^[8] ; Chengzhong,Yu ^[9]

作者单位： Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia; Children's Cancer Institute, School of Medicine and Health, UNSW Sydney, Sydney, 2052, Australia. Electronic address: zan.dai@unsw.edu.au. ^[1] Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia; School of Chemistry, UNSW Sydney, Sydney, 2052, Australia. Electronic address: qiaoyun.wang@unsw.edu.au. ^[2] School of Chemical Engineering, UNSW Sydney, Sydney, 2052, Australia. ^[3] South Australian ImmunoGENomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, 5005, Australia. ^[4] Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia. ^[5] Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen, China. ^[6] Australian Synchrotron, Australian Nuclear Science and Technology Organization, Clayton, VIC, 3168, Australia. ^[7] MOE Key Laboratory of High Performance Polymer Materials & Technology, School of Chemistry& Chemical Engineering, Nanjing University, Nanjing, 210023, China. ^[8] Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia. Electronic address: c.yu@uq.edu.au. ^[9]

关键词 Cancer immunotherapy Macrophage Nanocomplex Tumor metabolism